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"markedly affected" is correct and can be used in written English.
This phrase can be used to emphasize a transformation or change. For example: "Her confidence was markedly affected by the negative comments she received."
Exact(36)
Once transported to the stigma, the germination of the pollen grains is markedly affected by the chemical composition of the stigmatic exudate; e.g., pollen of an unrelated species will not germinate on the stigma.
The enzyme activity is markedly affected by variation in pH outside its optimum pH.
Quality of life (QOL) is markedly affected by multiple sclerosis (MS).
However, the IR modulation efficiency is markedly affected as a consequence of the increased metallic character of the semiconducting phase.
The performance of immobilized enzymes which catalyse H+ ion generating reactions is markedly affected by diffusional limitations on H+ ions.
From the simulation results, it is found that the outage rate of TLs is markedly affected by the model of the tower footing grounding system.
Similar(24)
The evolution of a member of a close double-star system can be markedly affected by the presence of its companion.
Case study: Most will get less The IFS gives an example of someone who is now 28 and whose entitlements would be markedly affected for the worse by the change.
It is shown that the underground electric fields are markedly affected by the ground conductivity.
Soil fertility parameters (N, P, K, Organic carbon) were markedly affected by different doses of sludge.
Meningeal cell morphology was markedly affected by nanometer level substrate topography.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com