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The purpose of the analysis at 18 and 24 months is to determine if any change is maintained once the patient has been discharged from the specialist depression disorder team.
In Xenopus, analysis of signaling by Activin, a TGFβ signal related to Nodal, has suggested a ratchet model: the response to the signal is maintained once the ligand has bound the receptor.
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The fiction of equality could not be maintained once power passed down to the emperor's closest male relative.
Others are altogether less sure whether momentum can be maintained once the circus has left town and political focus has dulled.
Accomplishment needs to be maintained once its established.
In view of the low levels of circulating antibody in adolescence, there is uncertainty if the high vaccine efficacy against carriage can be maintained once infant vaccines become exposed to HBV via sexual routes.
This was maintained once women with known complications were excluded.
As such, why such a separation would be maintained, once it occurred, is clear.
However, blinding will be not be maintained once randomisation has occurred.
In addition, there is no guarantee that incidence will be maintained once the actual trial starts.
In several cases, differences observed between disease sets and unconstrained samples are maintained once function is also considered.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com