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In contrast, in Ewing sarcoma, a chromosomal translocation involving a transcription factor inhibits the expression of the miRNA-cluster in which miR-125b is located, leading to repression of miR-125b expression [ 55].
3 IVS3+2T>C mutations can cause skipping of the whole of exon 3, where the trypsin binding site is located, leading to the loss of the trypsin binding site, 27 altered expression of SPINK1 protein in CP patients with the IVS3+2T>C mutation, affecting the protease/antiprotease balance within the pancreas.
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Thus, the mean reflection point calculated with the leading edge filter (Figure 5A: meanLE level) is located on the leading slope of the data distribution.
A cold front is located at the leading edge of the temperature drop off, which in an isotherm analysis shows up as the leading edge of the isotherm gradient, and it normally lies within a sharp surface trough.
The length of the plates is L, and the distance between them is D. The origin of the Cartesian coordinate is located at the leading edge of the lower plate (see Fig. 1).
According to military figures, the Tamazula municipality, where the Peña ranch is located, is the leading producer of marijuana and opium in Durango state.
For example, in the case of Borrelia burgderfori the first ORF is located in the leading strand, so it was included without any change to the sequence.
In chemotaxing cells, PtdIns 3,4,5) P3-binding myosin I is located at the leading edge.
In total, 59.6% of the predicted gene repertoire is located on the leading strands of the C. variabile chromosome, revealing a moderate gene-strand bias in this species.
Thus in genomes where GC3skew is detected on axis 1 of WCA, the axis scores can be used to predict whether the gene is located on the leading or lagging strands.
However, the iut/ iuc operon is located on the leading strand and on the counter-clockwise site of the replication origin in Sf301, but on the lagging strand and on the clockwise site in Sf8401 (Fig. 2c).
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