These administrative districts, named after the city gates, were termed berthae and were linked to maintenance and manning of the city walls.
In mice, DAZL function has been linked to maintenance of pluripotency [19], epigenetic programming in the embryonic germline [19], primordial germ cell/gonocyte survival [18], and is required for oogenesis and spermatogenesis [16].
Other mechanisms underlying the protective effects of Nrf2 were linked to maintenance of mitochondrial function [ 51].
More recently, separase and meiosis-specific cohesin have also been linked to maintenance of centriole cohesion during male meiosis [ 13].
Degradative capacity is linked to the maintenance of an acidic milieu in the lysosome, an energy dependent process requiring the vacuolar-type proton ATPase (V-ATPase) and other hydrogen pumps, which are required for activation of the proteases [43], [44].
This finding, together with the observed phenotypical consequences upon knock-down and the observed co-localization at MCIB RAD21 sites suggests that RAD21 is linked to the maintenance of ESCs through an association with pluripotency transcription factors.
It is believed that SCs, 24 h after activation, express Pax7 and MyoD, but then a proportion of them (around 20%) withdraw from cell cycle to return in a quiescent state (Pax7+ MyoD) that is linked to the maintenance of the SCs pool [32].
The process of apoptosis is often associated with mitochondrial fission, and mitochondrial fission is linked to the maintenance of mtDNA.
Regarding the former, it has also been demonstrated that H3K18 hypoacetylation is linked to the maintenance of malignant phenotypes and poor prognosis in cancer.
