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Shi et al. (2004) showed that LSD1 specifically demethylates histone H3 lysine 4, which is linked to active transcription.
Also, ORF5 encodes a protein similar to LSD1, which represses transcription by demethylating histone H3 at K4, whose methylation is linked to active transcription (Shi et al. 2004).
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Circular pupils were linked to "active foragers," or animals that chase down their prey.
In this context, tourism, recreation and leisure are linked to active engagement.
Given the neurological link of these neural tissues with control mechanisms, such as the vestibulo ocular reflex (VOR) and vestibulo collic reflex (VCR), it has been suggested that a well-developed flocculus could be linked to active predation in dinosaurs25.
This indicates that in visual search, dwell times are linked to active processing of features which in turn proceeds on a need-to-know basis [20].
Furthermore, consistent with our previous studies in vivo [9], UV inactivation of the viral nucleic acid hindered the effect of RSV on both NGF upregulation and apoptotic cell death, indicating that the changes observed in the neurotrophin pathways are linked to active viral replication and expression of the viral genome in the respiratory epithelium.
Most emergencies and clinical deteriorations were linked to active patient treatment – surgical and systemic therapy (chemotherapy and target therapies).
However, exosite binders may be linked to active site inhibitors to achieve highly potent and highly selective two-site binding inhibitors.
Th2 cells have been shown to be overrepresented in SSc tissues and to be linked to active disease compared to Th1 cells, since IL-4 has direct pro-fibrotic properties [ 22- 25].
An obvious inference from our data is that because TtPilF binds DNA, and because p[NH]ppA causes structural change in the oligomer, ATP hydrolysis by TtPilF would be linked to active DNA transport across the inner membrane.
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