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First, our approach of modelling the depth of coverage prior using small windows is likely suboptimal.
This method of combining ratings from different sources is likely suboptimal; however, in some cases, this was the only viable alternative.
A key message is that substitution of a long half-life benzodiazepine with a short half-life one is likely suboptimal.
The simple approach we used of filtering (JointSNVMix1) or modelling (JointSNVMix2) mapping and base qualities is likely suboptimal since they both do not consider technical artefacts such as strand bias.
It is possible that the underestimation of SV during fluid therapy may potentially require substantial correction for dosage regimen, since brute-force fluid administration based on linear SV-PP assumption is likely suboptimal.
Using the existing framework of the ICD9 coding schema allowed for rapid generation and quick interpretation from a known resource; however, it is likely suboptimal for some diseases and groupings.
Similar(54)
However, for frequent perturbations it is likely that suboptimal sequences are repeatedly chosen.
As much of the patient safety training is focused on behavioural and practice issues, it is likely that suboptimal practices have already been developed by this stage.
However, if the features encoded in the FFA serve primarily face detection, individuation processing in this area is likely to be suboptimal.
In view of this, simple adjustments using self-reported CPD metrics is likely to be suboptimal for teasing out direct effects on lung cancer risk and it is perhaps not surprising that effect sizes for many 15q25 lung cancer associations appear relatively unchanged when simple adjustments are made.
It is likely that the suboptimal context for the HIC translation initiation codon (CGGCCCAUGU) as well as the very long 5' UTR containing other features (e.g. a complex RNA secondary structure) also contribute to the low translation efficiency induced by the 5'-UTR of HIC mRNA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com