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These results suggested that p55PIK promoter activity is largely lost upon deletion of the sequence between −1243 and −839 of the full-length promoter.
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This is supported by our observation that at centromeres, de novo silencing upon clr4 + reintroduction is largely lost in sir2N247A mutant backgrounds.
Too bad the title's import is largely lost.
This pungency is largely lost in the film.
In the presence of Hedgehog pathway activation Hes1 activity is high but this activity is largely lost in the absence of Rbpj, suggesting that most of the Hedgehog-dependent Hes1 activity is dependent upon active canonical signaling.
The promise of a new generation is largely lost.
This resistance is largely lost after puberty, an association that seems causal.
And Mr. Waxman's focus on pardons past was largely lost in the hours upon hours of testimony on more recent grants of clemency.
But after Patco, that weapon was largely lost.
That explanation was largely lost in translation, however.
This appears to have been largely lost in Chadic and Omotic and completely lost in Egyptian.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com