Sentence examples for is largely localized from inspiring English sources
However, in contrast to the PhCl⋯NH3 system, calculations predict that the structure of the reactive intermediate corresponds to a distonic ion-radical complex, where the radical density is largely localized on the bromine atom.
Knockdown of endogenous PTK6 protein that is largely localized to the cytoplasm resulted in decreased PC3 cell proliferation.
Trio is largely localized near the membrane [62], while cytoplasmic Spg and Sos can be recruited to the membrane by their association with N-cadherin and Robo, respectively [9].
Under normal conditions, the transcription factor Nrf2, a primary transcription factor required for the induction of a battery of phase II detoxification genes through activation of antioxidant response element (ARE), interacts with the actin-anchored protein Keap1 and is largely localized in the cytoplasm resulting in the low basal expression of Nrf2-regulated genes.
Laser confocal microscopy in transgenic lines expressing n-syb-eGFP showed that fluorescence is largely localized in the mushroom bodies, the brain region involved in associative learning and memory, and to the antennal lobe of the brain region, which is responsible for olfactory function [Fig. 2A].
Therefore, GnT1IP-L that is largely localized to the ER does not inhibit MGAT1 activity.
As shown by multiple ultrathin sections of photoreceptors, RPGRIP1 localization was solely restricted to the CC, where it was largely localized throughout its ciliary submembrane region.
Although PDI-family proteins are largely localized to the endoplasmic reticulum, recent reports have described a cell surface localization and function of these enzymes [55] [57].
Confocal microscopy revealed that LCP NPs were largely localized in hepatocytes not Kupffer cells.
Intratumoral staining was largely localized to tumor cells at the periphery of the microtumor nodules surrounded by stroma and vessels (Figure 5).
After a 4-h incubation, PNAs were largely localized in the nuclei of the cells; the mechanisms involved are still unclear.
