The toxicity of synthetic amyloid-like peptides has been largely demonstrated and shown to depend upon their aggregation state.
Despite their lack of protein coding potential, ncRNAs have been largely demonstrated to regulate the majority of biological processes and have also been largely implicated in cardiovascular disorders.
In this rapidly changing scenario, treatment of brain metastases remains an high unmeet medical need, and the efficacy of immunotherapy in these highly dismal clinical setting remains to be largely demonstrated.
The fallacy of this view has been largely demonstrated in previous sections.
PBL has been successfully used in various different domains, and its benefits have been largely demonstrated (Savery 2006).
The preventive efficacy of frovatriptan has been largely demonstrated by randomized, double-blind, placebo controlled or open label studies [25 29].
The phytoconstituents including polyphenols, quercetin and flavonoids are largely demonstrated as important antioxidants and exhibit profound radical scavenging capabilities (Bravo 1998; Chu et al. 2000; Duthie et al. 2000; Gil et al. 1999; Middleton and Kandaswami 1994).
While the risk of crossing in front of a second train has been largely demonstrated and discussed previously [10, 11, 12, 13, 15], it might not be as important in the current crossing context at LCs in Brisbane (2014), given that often a single track is operated by a separate set of active controls (pedestrian gates and lights) which deactivate allowing crossing soon after a train had passed.
These results are not unexpected since extensive similarities among cestodes [21] [23] have been largely demonstrated in the past, and offer the possibility of using the respective antigen homologues for protecting against other cestodiases [5], [24], [29].
However, it has been largely demonstrated a strong association between CHC profiles and the reproductive status of females in ants [e.g. 27], [28], [51] [53] as well as in other social insects.
