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RNAi, which occurs in plants and animals, including humans, is key in regulating gene expression.
This coordinated response allows rapid and robust induction of mRNA messages that can enhance the CD8+ T cells' ability to inhibit virus upon antigen encounter.We show that mRNA stability, in addition to transcription, is key in regulating the direct anti-HIV-1 function of antigen-specific memory CD8+ T cells.
The phytohormone ABA is key in regulating plant stress responses and plays important roles in seed germination [ 24].
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These genes appear to be key in regulating radiation response and therefore these pathways or their upstream regulators may prove to be a good predictor of treatment outcome.
These results further suggest that an increase in influenza MOI in rDC following high vs. low dose infections may be key in regulating the magnitude of the adaptive CD8 T cell response [7], [8], [9], [11].
While this study did not examine how IGF1-IGF1R levels influenced cellular behavior, this more complex model also suggested IGFBP levels were key in regulating receptor-ligand complex levels.
The large number of plant Puf protein family members suggests that these proteins are key in regulating the stability and translation of a significant number of mRNAs in the cell.
Parrotfishes, or uhu in Hawaiian, are key players in regulating algae and reef life.
As mentioned earlier, μ- and κ-opioid receptors are key players in regulating pruritus in the central nervous system, but epidermal keratinocytes reportedly express these opioid receptors both in vitro and in vivo, 53 suggesting nalfurafine can exert its antipruritic activity through κ-opioid receptors in the epidermis.
Immune semaphorins are key players in regulating immune mediated inflammation.
Taken together, these results indicate that DREB2C and HsfA3 are key players in regulating the heat tolerance of Arabidopsis.
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