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'is irrespective of' is correct and usable in written English.
You can use it to express that something does not depend on a certain factor. For example, “This policy applies to everyone, is irrespective of their age.”.
Exact(59)
"Using automatic vehicle location, we will know where the nearest appliance is, irrespective of which station the appliance belongs to".
But it's always been a space for collaboration and creation that is irrespective of marketplace notions of genre.
"This is irrespective of whether certain shareholders cannot afford the assessment or do not get a direct benefit from the renovations," Mr. Sherman said.
But the Israeli prime minister says this is "irrespective" of his willingness, indeed his desire, to proceed with "parallel" talks with the Palestinians.
But Americans deserve to know what a quality person he is – irrespective of whether they agree with him on an issue or not.
Only when it recognizes the falconer and the glove as a source of food will it begin to become tamer, and this is irrespective of whether the hawk is captive-bred or taken from the wild.
And this behavior is irrespective of the GNPs aspect ratio.
That is irrespective of "startup DNA," even for century-old family owned businesses.
This is irrespective of the production quantity in one setup.
And this is irrespective of whether they are text ads or display ads.
This similarity is irrespective of the RZ12 index.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com