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"Such an animal model is invaluable for understanding the role of BRCA1 in familial breast cancer," says Andrew Futreal of Duke University Medical Center in Durham, North Carolina, a BRCA1 co-discoverer.
A firm grasp of evolution is invaluable for understanding our own species in addition to the rest of the biological world; however, not only does much of the American public reject evolution, but many thinkers within the scientific community resist its application to their own disciplines.
Such detailed knowledge is invaluable for understanding the speciation process [4], [23].
The evaluation of drug exposure data, especially free drug concentrations, is invaluable for understanding the relationship between drug levels and the degree of hERG blockade (Supporting Information Table S1) and QT interval prolongation in vivo, and helps develop a quantitative assessment of concordance based on exposure parameters (Redfern et al., 2003).
Evaluating simulation models for alternative compiler and operating system configurations is invaluable for understanding model performance constraints and for improving model robustness, portability, usefulness, and flexibility.
Such energy partitioning is invaluable for understanding of the ligand binding mechanism, and is impossible to obtain experimentally.
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Such secret files have been invaluable for understanding the dictatorships in Chile, Guatemala and El Salvador and Washington's role in backing them.
Furthermore, studies of pollination are invaluable for understanding the evolution of flowering plants and their distribution in the world today.
The fact that the results obtained with C. elegans appear to have strong similarities in human beings suggests that not only will C. elegans prove an invaluable model for understanding the fundamental biological changes seen during spaceflight but that it may also be invaluable for understanding those changes associated with human health concerns in space.
The genomic organization and gene functionality of M. tuberculosis are invaluable for understanding the slowly growing pathogen.
The transgenic models for amyloid and tau pathology have not, however, substantiated this hypothesis to the fullest, although they have been invaluable for understanding molecular mechanisms of amyloid peptide generation, amyloid pathology, repercussions on cognition and behavior [13] [17].
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