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In the context of conjugation, contact between T-cells and APCs is initially induced by chemokines followed by TCR induced 'inside-out' signals that leads to a major increase in the number of TCR-MHC peptide interaction events.
The results demonstrate that the nonspecific binding of DNA to M.HhaI is initially induced by electrostatic interactions.
In this general pathway, it is believed that SNAIL 2 is initially induced, leading to the activation of TCF4 and FOXC2.
In the first group of pioneer MNs, Pea3 expression is initially induced by glial-derived neurotrophic factor (GDNF), produced by the target muscle [ 31].
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Next, we hypothesized that resistance-related genes are initially induced through carboplatin treatment in A2780 tumors (initial response) and show higher basal expression level in vehicle-treated A2780cis tumors compared to vehicle-treated A2780 tumors (acquired resistance).
Consistent with this hypothesis, we found that the endogenous levels of RASSF9 mRNA were initially induced when keratinocytes were exposed to a calcium concentration of 2 mM (differentiation-inducing conditions) for 1 day, but were thereafter reduced as differentiation progressed (Figure S10).
Anaesthesia was initially induced by intramuscular injections of ketamine (10 mg/kg) and midazolam (1 mg/kg) to allow preparation and handling of the animals and maintained with a mixture of ketamine (5 mg/kg) and midazolam (0.5 mg/kg).
To overcome the limited surface that fungi can inhabit at low water availability due to restrained growth, a MC optimal for growth should be initially induced, followed by a drying period to stimulate pigmentation.
In the case of convective mixing induced by QB, because forcing of QB is confined to the cloud base and is maintained, strong small eddies are initially induced around a thin unstable layer at the cloud base and spread to the middle and upper parts of the neutral layer.
Subcultures were initially induced under conditions of physiological osmolarity and normal human body core temperature (37°C).
Previous work has demonstrated that several of these organ primordia are initially induced by signals from neighboring mesoderm.
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