The problem is that a voting system that is based on physically recounting chits of paper is inherently error-prone, and in a close election like this, the errors are too large for the process to determine a winner.
Estimation of unigene overlap is inherently error-prone because best BLAST hits are not necessarily orthologs.
However, there is a 'dark side' to DNA repair because the process by which the replacement DNA is synthesized is inherently error-prone.
We might expect that high replication errors occur with hyperactive pol ι in normal DNA replication because pol ι is inherently error-prone in its general nature.
Of note, NHEJ is inherently error-prone and mutagenic, because this process is unable to faithfully restore the original DNA sequence, as opposed to HR, and because NHEJ itself can introduce sequence changes during repair.
However, the raw data generated from the PacBio RS platform is inherently error-prone, with up to 17.9% errors having been reported [ 6], the majority being indel events, caused by incorporation events or the intervals between them being too short to be reliably detected [ 4].
Taken together, these results suggest that in the absence of pre-existing centrioles, de novo centriole synthesis can occur, largely independent of SAS-6 self-oligomerization, but the process is inherently error-prone, and may require the presence of pre-existing centrioles to achieve high accuracy.
However, as the mobility of the pedestrian is mostly controlled by vision in practice, an individual might detour slightly from the Euclidean shortest path connecting two given nodes (i.e., beeline path), as vision-based navigation is inherently an error-prone method.
Pol ι is inherently very error-prone in nucleotide insertion, particularly opposite undamaged template bases G and T, respectively, yielding misinsertion of either dTTP or dGTP at a frequency of about 0.1 and 1 (relative to the correct nucleotide insertion), which is ascribed to its unique active site and related non-Watson Crick base pairinon-Watson Crick
Formation of disulfide bonds in a protein with more than two cysteines is inherently fraught with error and can result in incorrect disulfide bond pairing and, consequently, misfolded protein.
