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At the same time, southward flow of Tibetan middle crust is inferred to play a role in the formation of the Greater Himalayan Crystalline Sequence (Beaumont et al. 2001).
The LSG, 237NG, is inferred to play a role in glycerophospholipid metabolism and cytokine signaling, and is one of the hub genes.
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ATM therefore can be inferred to play a critical role in immunoregulation after airway mucosal damage.
These central parts are inferred to play a key role in the structure and/or function of their TLRs.
The central parts are inferred to play a key role in the structure and/or function of their TLRs.
If the deletion of an HDAC gave rise to FLO1 transcription it could be inferred to play a role in FLO1 gene repression.
IGFIR signaling has recently been inferred to play a role in tumor growth and the invasive and metastatic ability in various carcinomas in vitro and in animal models [ 18].
Two iron-containing alcohol dehydrogenase genes (adh, Cbei_1722 and _2181) were inferred to play key roles during primary alcohol production in C. beijerinckii 8052 by comparing them with their previously characterized orthologs in C. beijerinckii NRRL B592 [ 9, 16, 17].
At that time, substance P was thought to be a fundamentally important signal for pain neurotransmission (hence the substantial efforts to develop substance P receptor antagonists), and the coincidental reduction of substance P content was inferred to play a causal relationship in capsaicin-induced pain relief.
Of these CDS, 80% could be assigned a function and, as expected, a large proportion was inferred to play part in basic bacterial functions such as synthesis of proteins, nucleosides and nucleotides, amino acids, co-factor prosthetic groups and carriers, and of the cell envelope (see Additional file 2 for the full listing).
The results of the functional divergence analysis suggested that caleosin genes should be significantly functionally divergent from each other, especially with respect to the three amino acid residues (70R, 88 L and 106A) identified by both PAML 4 and DIVERGE 2.0 analyses, which were inferred to have played important roles during evolution.
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