The major mediators of IFNγ-induced signaling, STAT1, JAK2, and IRF1, were induced together with several factors that may regulate STAT and JAK function (CISH, NMI, PTPRC, PTPRO, SOCS1) [34].
Other cell repair genes and attenuators of cell death (AtBI1, BAG3, BAG7, autophagy8h, NDP-kinase, NUDT7) were induced together with cell death genes (ACD2, RCD1, VAD1, MCP1b) and might signify strong cellular damage and links between hormone and stress signalling after IR [127].
METHODS: DM and PD were induced together in 15 rats (group 1) by streptozotocin injection and ligature induction.
The UPR markers XBP1 and ATF6 were induced together with genes involved in ubiquitin-proteasome and lysosomal proteolysis.
Although many of these adaptations promote tumor survival individually (106), they probably are induced together as a result of gene dosage.
Proapoptotic and antiapoptotic members of the Bcl-2 family (Bax, Mcl1 and Bcl2l) were induced together with the downstream effector of the intrinsic pathway Apaf1.
PtAMT1-2 inducedced by ectomycorrhizal symbionts together with PtAMT1-4 and PtAMT1-6 (named PtAMT1-3 in Selle et al.[ 69], but PtAMT1-6 in Couturier et al. [ 6] and at 'Phytozome').
When SOC1 is induced at the shoot apex, SOC1 together with AGL24 directly activates LFY.
Differentiation of Th 17 cells in the mouse is induced by transforming growth factor beta together with either IL-6 or IL-21, followed by self-amplification involving IL-21 and then stabilisation by IL-23.
