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As such, the existence of these non-native medium-range NOEs, together with the chemical shift deviations, suggesting that in V22-SH3, the non-native helical conformation is indeed populated over the second region, but not the first region as observed in the wild-type SH3 domain at pH 2.0 and 4Ala mutant at pH 6.5.
Further analysis of the NOE connectivity pattern indicates that except for the missing residues, sequential dNN i, i + 1) and medium-range dRN i, i + 2) NOEs could be observed over the majority of the sequence, suggesting that the non-helical conformation is indeed populated to some degree.
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The life was indeed populated by a host of secondary characters, and the story told at length demanded some judicious paring.
Indeed, the observation that the residence times of SRP on RNCs containing exposed signal sequences between 40-50 acids andds and 60-70 amino acids are two-fold shorter than that on RNCs containing exposed signal sequences between 50-60 acids acimplymply that binding intermediates with average lifetimes shorter than that of the final complex are indeed populated.
A century ago, Palestine, part of the Turkish empire, was indeed thinly populated.
Moreover, while Brooklyn was named for a Dutch town and was indeed heavily populated by the Dutch in the 17th century, their power to enslave anyone there pretty much vanished after 1664, when the English seized the Dutch West India Company's settlement in New Amsterdam.
Using lineage tracing experiments, the authors conclude that Dlx5 is indeed transiently expressed in precursors that will populate the maxillary arch, and also provide support for the Hinge and Caps model.
Take, for example, the panoramic "Oz," framed in patchwork road maps, which gives us a dusty plain populated by people standing on mountains of possessions, as if bent on proving that every man is indeed an island.
I am, indeed, indeed.
If professional, idealized magistrates of the sort Farhadi depicts do indeed populate the country's courts, they must at the very least be keeping their heads down.
The results of these experiments suggest that STIM1 indeed populates ER-PM junctions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com