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[Author's response: Assuming extensive gene loss during emergence of certain lineages is indeed emphasized in our presentation; if the old idea of emergence of Bacteria and Archaea by "streamlining" of a more sophisticated ancestor is correct, it must have involved extensive gene loss indeed.
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It is indeed important to emphasize that animal placenta does not model the human placenta and its physiology well.
Authors' response: This paper is indeed relevant because it emphasizes that de novo synonymous mutations are likely to be a good control set; we now cite this reference in the discussion of this issue.
If the linear BDIM is indeed a realistic evolutionary model, this emphasizes the critical role of innovation in maintaining the balance (steady state) in genome evolution.
Thus, as a proof of concept, our trial emphasizes that it is indeed possible to titrate and individualize novel therapies in critically ill patients.
And by emphasizing wireless connectivity, Motorola is indeed onto something.
Neither of the two fragments induced membrane tubulation emphasizing that membrane interaction is indeed required for this phenotype.
Interestingly, Hap1p is indeed included in the cell-cycle module (module 4), emphasizing the close relationship between the heme group and developmental processes.
There is, indeed, much in Reflections besides the elements that have been emphasized here (and indeed much in Burke's later views on the Revolution which is not in Reflections): but without those elements, the book, and Burke's understanding of the Revolution would have been impossible.
But he emphasizes that "the frequent persecution of magicians is indeed a recent phenomenon.
Multiple frameworks of family processes emphasize that coping with stressors and successful maternal adjustment is indeed possible, but that when it fails, families can experience periods of crisis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com