However, it is increasingly apparent that they represent important sites for electrophilic adduction with respect to both the degree and the biological significance of their modification.
As we move forward in the new, rapid economy of tomorrow, it is increasingly apparent that equality is more than "good" for business -- it is absolutely essential.
For example, it is increasingly apparent that substantial subpopulations of randomly conjugated ADCs show little, if any, therapeutic activity, yet account for most of the toxicity.
On the 20th anniversary of the CRC, it is increasingly apparent that good governance is a prerequisite for realizing child rights – and that it must be a greater focus of international attention in order to achieve the ambitions embodies by the Convention.
We want someone like the woman who warned an audience at the Edinburgh Festival three months ago that "Profit without purpose is a recipe for disaster… It is increasingly apparent that the absence of purpose – or of a moral language – within government, media or business, could become one of the most dangerous own goals for capitalism and for freedom".
Animals harness this diverse bacterial metabolism for their survival, and it is increasingly apparent that this is a widespread phenomenon on both land and sea [10].
In lymphomas, it is increasingly apparent that the microenvironment is an essential player not only for lymphoma pathogenesis but also for disease progression and therapy resistance.
Thus, although it is increasingly apparent that the class I HDAC enzymes are clinically relevant for cancer, this is less established for the class II enzymes.
