For another RTX toxin, Actinobacillus actinomycetemcomitans leukotoxin (Ltx) it was recently shown that cells that do not express lymphocyte-associated antigen-1 (LFA-1) receptor molecules failed to accumulate Ltx in their raft fractions [18], suggesting that the association of Ltx and LFA-1 within lipid rafts was essential for Ltx to be in rafts.
These results suggest that the increase in Fas protein induced after MS-275 treatment was in lipid raft microdomains rather than the non-raft regions of the cell surface.
GM1, which is abundant in rafts, has been recently reported to accumulate in the glycosphingolipid-enriched microdomains of mitochondria-associated endoplasmic reticulum membranes, linking endoplasmic reticulum stress to Ca2+-dependent mitochondrial apoptosis.
I was in a raft with four Dutch guys and our guide.
You're in a raft floating down a raging river.
I was in a raft, attempting to paddle, spacing out.
This strategy has been observed for the CD30 protein which is located in rafts, whereas the metalloprotease responsible for its shedding, ADAM17, is excluded.
We believe that raft association of flotillins is essential for its uropod localization, as uropods are enriched in raft lipids [9].
The BK channels seem to be in lipid rafts in the plasma membrane apposed to the sER.
Sessions are cofacilitated by two members of the rheumatology team (eg, nurse, OT) who have been trained in RAFT (tutors).
Certain proteins are enriched in rafts, others are embedded in the membrane surrounding the rafts, and some proteins can shuttle between raft and non-raft membrane compartments, depending on the functional status of the cell.
