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In the free helicase domain structures motif V, an important RNA backbone interaction site [19] [22] is in a binding incompetent conformation.
Additionally, Sebio et al. showed a LCS6 polymorphism in the 3′-UTR of KRAS, which is in a binding site for Let-7, may serve as a predictive marker of anti-EGFR treatment in KRAS wild-type and BRAF wild-type patients [ 65].
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The likely role of Thr171 phosphorylation is to orient these five residues so their side-chains are in a binding competent mode for interaction with an unidentified RNA processing factor.
It is worth noting that the isolated output domains of L. pneumophila CdgS9 and P. fluorescens LapD cross-link to LapG readily, suggesting that they are in a binding-competent state, which is in agreement with our crystallographic analysis.
The book on the left is in a later binding than the one on the right, with some added edge gilding.
The first SNP is in an HSF1p binding site, but modifies a position where any nucleotide can be found.
rs67164370 is in a 3'-UTR miRNA binding site of the KRAS oncogene and is a candidate for epithelial ovarian cancer (EOC) susceptibility.
Joseph tells his brothers about a dream: "We were in a field binding sheaves, when my sheaf stood up.
The way American Airlines is trying to block our election makes me realize that our rights need to be in a legally-binding contract.
The assay indicated that the non-stimulated TCR complex was in a non-binding conformation, which we called closed-CD3 [33].
The c. -61G>T is located in a binding site for the transcription factor P300/CBP.
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