Ballast water is unlikely to be a relevant vector (Herborg et al. 2009) due to the very short larval phase of the species, while hull-fouling in fast-moving vessels may be improbable due to low attachment strength (Murray et al. 2012).
Over longer temporal scales, encroachment of extra-local species is improbable in our study region due to the vast expanses of low-elevation sagebrush steppe, effectively creating 'sky islands' of conifers that are common throughout WNA (e.g., O'Connor et al. 2014).
Therefore is improbable that an absolute over-dosage due to any procedural change could be the cause of the observed adverse effects.
Due to the fact that it is improbable that different protein molecules may have the same physicochemical properties (pI and MW), proteins are efficiently separated by 2-DE rathan than 1D-SDS PAGE [ 2].
Thus, it is improbable that they inform patients appropriately on the risk of adverse events due to drug administration.
As a result, it is not possible to exclude the possibility that the changes observed were due to an unknown factor, though in context, this is improbable.
While it could be argued that the observed gains, or a substantial proportion of the observed gains, were due to maturational or other effects, we would contend that this is improbable for several reasons.
Due to the high rate of mineralisation, an accumulation or formation of relevant metabolites is improbable.
As described in the section 'Effect of disturbance exclusion', however, an increasing competitive milieu due either to litter accumulation or more vigorous growth of plants not subjected to regular management is improbable in a less productive, dry meadow.
As it is improbable that many lipids accumulate within lysosomes a short time after transfection, it is plausible that the alteration of MCOLN1 function due to overexpression is responsible for impaired autophagosome maturation.
