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It "would be impossible" to replace Mr. Jain, he said, saying that "we won't find a substitute for him".
With keys to a classroom typically not given out to substitute teachers it is impossible to meet this requirement.
Also, it has been established that the mean flux over an area is a 'sufficient' flux statistic; it is impossible to obtain better predictive power by substituting the median flux, by adding standard deviation, or by using quantiles of the flux distribution.
Unfortunately, the required measured data, typically distillation and other curves, are often incomplete and it is impossible to obtain directly the 'phase portraits' needed to establish the substitute mixture.
Furthermore, if it is impossible to demonstrate the equivalence condition, then other considerations and evidence can be substituted to support the assumption of a causal relation (see below).
"It is impossible to forget".
It is impossible to know.
It is impossible to predict.
He is impossible to dislike.
It is impossible to relax".
It is impossible to tell.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com