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YkoW is hypothesized to interact with dsDNA ends.
Previously, based on its impact upon the secretion of CupB1 and CupB5, CupB4 is hypothesized to interact with CupB6.
The diapause hormone receptor is a G-protein gamma-subunit homolog, which is hypothesized to interact with the PBAN receptor, and has been reported in the PG transcriptomes of A. segatum [ 37] and H. virescens [ 38].
The LRSAM1 gene encodes an E3 ubiquitin ligase that is hypothesized to interact with proteins involved in endosome to lysosome trafficking, a pathway that has recently been implicated in the pathogenic mechanism underlying some CMTs.
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GST variants are hypothesized to interact with PAH exposures, although previous research has been inconclusive on a possible interaction between GSTs and PAH with respect to breast cancer [ 20, 21].
This representation may allow for the most interesting observations to be made: compounds that are predicted to modulate similar protein targets, and thus potentially share similar modes of action, are clustered together; if similar interactions are observed consistently between clusters, the underlying modes of action of each cluster might be hypothesized to interact as the cause of the synergy.
In the host cell, effectors are hypothesized to interact with specific host molecules, which are subverted in order to benefit the infecting Salmonella [1].
If an uncharacterized locus consistently assorts with soil ion content, for example, then it can be hypothesized to interact with this environmental variable to determine fitness.
These repeats have been hypothesized to interact with the intracellular cytoskeleton and act as a spring to open TRPA1 when under mechanical stress [11], [12].
On the basis of this structure LOX-1 has been hypothesized to interact with ox-LDL with a 3∶1 stoichiometry [4].
Indeed, the PilT protein of the pathogenic Neisseria meningitidis has been hypothesized to interact with the T4SS due to its limited homology to the DotB protein of the Legionella T4SS [167].
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