Sentence examples for is highly rugged from inspiring English sources

The folding landscape is highly rugged, with several energetic bottlenecks that frustrate the folding process.

Our study illustrates that the enzyme's adaptive landscape is highly rugged, and different functional sequences may constitute separate fitness peaks.

Instead, the folding transition state is likely reached via multiple pathways, providing further evidence that the apomyoglobin folding landscape is highly rugged and involves much energetic frustration.

These observations suggest that the code fitness landscape is highly rugged, i.e., consists of numerous fitness peaks of, approximately, the same height.

The pervasiveness of RSE in TEV genome suggests that its adaptive fitness landscape is highly rugged, and thus the virus may get easily trapped in local adaptive peaks.

The apomyoglobin folding landscape is highly rugged, with several energetic bottlenecks that frustrate folding; relief of any one of the major identified bottlenecks is insufficient to speed progression to the transition state.

The range is extremely rugged and glaciated.

However, a major hurdle is the removal of sturdy and rugged lignin component which is highly resistant to solubilization and is also a major inhibitor for hydrolysis of cellulose and hemicellulose.

The important thing was to make sure it was rugged and durable because African roads are highly degraded," he said.

The project includes a large number of tunnels and bridges which are to be implemented in highly rugged and mountainous terrain.

This is predicted to produce a highly rugged adaptive landscape, in which many adaptive pathways are inaccessible [ 27, 28].