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The molecular signaling underlying ischemia reperfusion and inflammatory response is highly intertwined and includes pro-inflammatory as well as cardioprotective elements.
These finding suggest that M-hMPV plays a central role in the inflammatory response initiated by the host innate immune system and is highly intertwined in the mechanisms of respiratory pathogenesis.
In complex organisms, such as mammals, it appears that the circadian clock is highly intertwined with nuclear receptor metabolic gene networks.
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In this episode, the girls' engagement in academic discussion and play were highly intertwined.
Although the European powers divided Samoa in two at the turn of the 20th century, the two Samoas have always been highly intertwined through culture, language, family and economics.
Thus, the molecular signalling that underlies tissue ischemia and the inflammatory response seem to be highly intertwined.
In parallel, it became clear that "sex" and "gender" are highly intertwined, leading some researchers to use the combined term "sex/gender" (e.g., [ 60, 61]).
Given that memory processing and motivation systems are highly intertwined (Phillips et al., 2008; Wise, 2004), further investigations are required to uncover the exact neural mechanisms by which testicular hormones influence adolescent NOR performance.
In most organisms, competition for limited resources and social interactions are highly intertwined, which makes it difficult to disentangle the effects of social traits from other life history traits [ 20].
Taken together with findings of other reports as to the significance of plasticity-relevant factors such as the NMDA receptors and protein synthesis for place cell responses, this suggests that synaptic plasticity and place cell encoding may be highly intertwined.
A second consequence is that the four helices of the BASS domain are highly intertwined, in a manner reminiscent of the plectonemic coiling of the two polynucleotide chains of a DNA double helix, far more so than the simple association of two anti-parallel side-by-side dimeric coiled-coils proposed previously (Kashina et al., 1996a; Acar et al., 2013).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com