The reason is that small-effect alleles despite appearing more frequently than large-effect alleles have only small effects on fitness (and are, hence, often lost due to genetic drift), while large-effect alleles might be removed because they "overshoot" the optimum (Kopp and Hermisson 2009b).
Teachers were also reported to be dying from HIV/AIDS related causes and they are not being replaced hence are lost to the educational system.
Patient was referred to a peripheral cancer centre for logistic reasons and hence lost to follow up.
Unclear vital status and hence lost to follow-up were 88 persons.
In contrast, genes that are less crucial for development and survival experience less selective pressure in the form of balancing selection, and are hence permitted to be differentially lost in vertebrate lineages (Lynch et al. 2001).
The remaining 22 women who dropped out were categorized as unexposed and hence were lost for the control group.
The low number of responses may have in part resulted from the Chiropractors Board of Australia invitation notice being embedded in their newsletter and hence being lost amongst the other information.
This is then compounded by the entity modification process merging these false positives with adjacent true positives such that the true positive is also lost, hence the loss in both precision and recall.
Although recombinant adeno-associated viral (rAAV) vectors are promising tools for gene therapy of genetic disorders, they remain mostly episomal and hence are lost during cell replication.
This situation would, in effect, be similar to the gene being lost; hence, it would be subject to negative selection.
