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Cys-Gly is further cleaved by a dipeptidase (for review see Ref. 1).
In 4C procedure, the fragment is further cleaved by a second restriction enzyme and subsequently religated to form DNA circles.
P1 is further cleaved into the structural proteins VP4, VP2, VP3 and VP1.
APP is cleaved by β-secretase resulting in the generation of the C-terminal fragment C99, which is further cleaved by the γ-secretase complex generating different Aβ species.
A CRISPR cassette is transcribed as a long precursor RNA molecule that is further cleaved into small fragments (crRNA), each containing one complete spacer.
Smaller asLSU- γ-hybridizing fragments ranging from ∼40 150 nt were also detected in 80S and polysome fractions, suggesting that part of the asLSU- γ RNA is further cleaved.
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This membrane-anchored chemokine can be further cleaved by specific proteases, hence released in a soluble form [40], [41], which has been proposed as a biomarker for acute coronary syndromes [42].
In the cytoplasm, these pre-miRNAs are further cleaved by the endonuclease (Dicer) generating mature miRNAs.
C99 can be further cleaved by BACE1 at its Glu site to produce C89 [ 70].
The 65 kDa core protein can be further cleaved by a furin-like convertase into a 40 kDa protein.
GPC3 is first processed to the 65 kDa core protein, which can be further cleaved by a furin-like convertase into a 40 kDa protein.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com