Sentence examples for is functionally critical from inspiring English sources

Our data extends this observation by demonstrating that inhibition of Bmi-1 is functionally critical for the miR-128a growth suppressive function.

Various sulfotransferases and sulfatases with differing specificities control the pattern of HSPG sulfation, which is functionally critical.

RAD51 multimerization is functionally critical for HR in cells.

Our study demonstrates that the TWIST1 WR domain is functionally critical to TWIST1-induced cell invasion.

This region is functionally critical due to the splicing of exon 10.

To determine whether AS is functionally critical for myotube hypertrophy, the influence of AS (10 ng/mL) on myotube thickness was examined.

And third, it is not well established that abdominal air sacs were either first to evolve or are functionally critical to unidirectional ventilation.

We predicted that for a residue to be functionally critical, it should not only have a high CRE score but should also be highly conserved in the DHA1 family.

Significantly the amino acid residue at position 5 (N) proved to be functionally critical for the immunostimulatory properties of VHCDR3, as its substitution by alanine abrogated TNF-α production.

An extrapolation of these predictions to the entire DHA1 family members as validated from previously published data shows that these residues are functionally critical in other members of the DHA1 family also.

The application of our method to another MFS-MDR transporter EmrD of E. coli further reveals that residues which are shown to be functionally critical were found to have high CRES score and could be matched with critical residues of CaMdr1p.