"The safeguard mechanism is expected to fail to 'safeguard' the ERF investment, with abatement purchased by the ERF expected to be fully displaced by a significant rise in emissions elsewhere," it says.
Binding was fully displaced by the type 1 NT-R-selective antagonist SR48692, indicating that the NT-R in the tumors are of the type 1 NT-R subtype.
It is also possible that U2AF is not fully displaced, but that its interaction with the 3' splice-site is weakened in the presence of PUF60.
Later analyses showed that CpxI is not fully displaced but there is competition between synaptotagmin-1 and part of CpxI for binding to the SNARE complex on membranes (Dai et al., 2007; Xu et al., 2013).
The influence of the day-night cycle is never fully displaced (standard artificial lighting is not strong enough to inhibit the release of melatonin), and the performance of night shift workers usually suffers.
The great conciliarists active at the Council of Constance attempted unsuccessfully to balance these two emphases, and even in the modern period, despite the growing prominence of ultramontane views and their eventual triumph at Vatican I, the collegial concern was never fully displaced.
Thus the conclusion that over-expression of an hTERT allele, that fails to localize to telomeres, displaces endogenous hTR from telomeres is fully supported by the data presented.
That's why the Women's Refugee Commission will be advocating that the concerns of the displaced be fully integrated in the CSW's delegates' deliberations and in their commitments to action.
The Web may not be ready to fully displace traditional methods just yet, but it could make life simpler.
Mr. As Sy also stressed that the affected populations – including traditional pastoralists and herders, local communities, refugees and internally displaced persons – should be fully involved in designing, implementing and evaluating programmatic solutions to the problems they face.
