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This is of importance in breast cancer, a malignancy in which a given nodal metastasis is frequently smaller than the involved node by itself.
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In fact, Amazon regularly turns a profit, although it is frequently small in comparison to its revenue, and Bezos owns the Washington Post personally, so its profit or loss wouldn't affect the tax Amazon pays.
Further, the diverticular ostium is frequently small and easily missed [6, 13, 20].
The number of individuals carrying a given CNV at a known gene locus is frequently small, so conventional association studies based on statistical analyses cannot always be performed.
Furthermore, the diversity of these skeletal elements is frequently small, patterns in arrangement are hardly detectable, and environment-induced morphological variability makes their unambiguous interpretation difficult (see e.g. [2], [3]).
The number of individuals carrying a given CNV at a known gene locus is frequently small.
Many of the member firms are also registered in the NEF database, and companies not registered are frequently smaller and medium-sized firms.
As can be seen in the example in Figure 4, the dorsal slope was frequently smaller than the ventral one in the analyzed pressure range (PEEP − PEEP +5 cmH2O).
Here, the axonemes were easily visible (arrowheads, Figures 1h and k); however, the mitochondria were frequently smaller than those in the control cysts, containing electron-dense material and a striking vacuolisation (arrows, Figures 1h and k).
They are frequently smaller than 200 nt in size, and act to regulate mRNA translation/decay but can also bind to proteins and thereby modify protein function (recent reviews [ 1, 2]).
Interestingly, despite their methodological differences, the systematic review found that the differences in results between RCTs and non-randomised studies are frequently smaller than those between RCTs or between non-randomised studies [ 7].
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