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The hallmark clinical and genetic heterogeneity of mitochondrial disease is frequently compounded by the lack of clear genotype phenotype correlations, although biochemical assessment of respiratory chain complex activities in skeletal muscle is often helpful in guiding molecular genetic diagnostic testing.
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Prospective adopters shy away from older children who have had longer to accumulate emotional and behavioural difficulties caused by living with neglectful or abusive birth parents, problems which are frequently compounded by numerous disrupted foster placements.
The problems of exposure to occupational hazards, however, are frequently compounded by preexisting malnutrition and a high incidence of infectious disease.
Even worse, the effects of substandard design are frequently compounded by substandard maintenance over time, creating a "wrong part of town" even if things didn't start out that way.
It's taxi fare, and it's staying in hospital… (Caregiver, 11a) Treatment-related expenditures were frequently compounded with a loss of family income.
Furthermore, the ICU is frequently a hectic environment, compounding the likelihood of human error.
In spite of its complex structure, the Cu-rich γ1-Al4Cu9 compound is frequently observed in Al Cu processing.
Nevertheless, as is frequently done with 123I-compound in current clinical use, a thyroid-blocking agent could be administered to further reduce thyroid exposure.
Within the United States (US), natural ACTH is used, whereas outside the US tetracosactide, a synthetic ACTH compound, is frequently used.
We suggest that the aglycone of ciwujianoside E may be formed from 30-noroleanolic acid, which is frequently observed in natural compounds [ 16] and may be derived from 30-nor β-amyrin.
Although chemical stress due to the toxicity of precursor and product compounds is frequently encountered in microbial bioprocessing applications, the involvement of sRNAs in this process is not well understood.
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