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This event is favoured through an increase in expression of the suppressor of cytokine signalling SOCS1 protein, a known positive regulator of ubiquitination and degradation of JAK proteins.
As the composition of the RA synovium includes elevated levels of inflammatory cytokines on a hypoxic background, a strong and continuous presence of HIF transcription factors is favoured through increased HIF-α mRNA levels and protein stabilisation.
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However, if enough genetic variability is retained by the population, less inbred individuals, or individuals not carrying deleterious alleles can be favoured through selection.
It has also been suggested that bacterial sliding motility might be favoured through the secretion of surfactant substances from cells [ 21, 22].
By not contesting seriously in the other party's safe districts, by maintaining one's own safe districts, and by carving competitive districts up in such a way that one's own party is favoured (generally through legislative apportionment), party managers advance their own party's interests but often harm other social, economic, and political interests that need representation.
A search of the Cambridge Structural Database indicated that Ltri resulting from nitrogen bound amide hydrogen metal substitution is favoured over chelation through the amide oxygen atom.
Temperature has also a positive effect on the dissociation of O2 to form Oads, consequently, the formation of NO2 is favoured by temperature through the oxygen dissociation.
The mechanism by which liquid crystalline order is favoured can be illustrated through an analogy between molecules and grains of rice.
Induction hardening is a useful method for improving resistance to surface indentation, fatigue and wear that is favoured in comparison with through hardening, which may lack necessary toughness.
In the first case, vicariance is favoured when incorporating area connectivity through time (TS) but dispersal is recovered by adding the parameter j (founder-event or long-distance dispersal speciation).
This "negotiation through extremism," as it has been described, is favoured self-defeatingly by both sides.
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CEO of Professional Science Editing for Scientists @ prosciediting.com