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Manual validation is the gold standard approach to confirm accuracy of database identifications, but is extremely time-intensive.
Developing in a dark room is extremely time-intensive.
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Since the PSSM-b classifier uses 6000 variables, the predictions are extremely time-intensive while the performance is as good as the other two classifiers; this model has not been put up on the web-server.
Another area that they're active in is around Wikipedia — human-written summaries and maintaining these summaries is extremely time intensive and Primer AI has formulated approaches to creating and maintaining pages.
It also required the instructor to design application activities beyond what was currently being done in the classroom, a process that all educators know is extremely time intensive.
However, both techniques are limited to large and relatively superficial lesions and are extremely time intensive and have limited anatomical coverage.
These studies are considered the gold standard; however, they are extremely time intensive and costly and place substantial burdens on participants.
The reasons why guidelines are not developed following the established evidence-based guideline development methods are not clear, though the recommended process is extremely time and resource-intensive [ 3, 16- 18] and requires a specific set of skills in identifying, appraising and synthesising research.
Given that map-based cloning of candidate genes is extremely time and resource intensive, even for model species with abundant resources, the possibility of using association mapping as a tool for cloning genes of functional relevance has the potential to accelerate genetic improvement of the complex perennial Populus.
However, this procedure is extremely time-, landr- and cost-intensive and can be realized only in very few clinical cases.
But, he concedes, MDA is extremely time- and labor-intensive, especially because it entails convincing healthy people to take drugs and have their blood drawn repeatedly.
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