Sentence examples for is extensively established from inspiring English sources

The correlation of physiological sensitivity to insulin (vis-à-vis glycemic regulation) and longevity is extensively established, creating a justifiable gerontological interest on whether insulin sensitivity is causative, or even predictive, of some or all phenotypes of slowed senescence (including longevity).

Therefore it comes as no surprise that the approximate controllability for various control systems has been extensively established in the literature; see [3 8] and the references cited therein.

In the last decades, it has been extensively established that multicellular spheroids represent an efficient model to validate effects of drugs and treatments for human care applications.

Crosstalk or reciprocal regulation between hormone-dependent pathways, including ERα- and AR-mediated signal transduction, and NF-κB signaling has been extensively established at multiple signaling nodes [43], [44], [45].

Therefore, investigations focused on inhibiting either excessive generation or hyperactivity of BACE1 are extensively established on account of alleviating the symptoms or even eradicating of the disease in early stage.

Given that the lack of P. falciparum-encoded microRNAs and microRNA processing machinery has been extensively established, we did not anticipate microRNA sponge roles for P. falciparum circRNAs [ 39, 40, 58].

Urine as an important source of disease biomarkers has been well established and is extensively used in diagnostic medicine [78].

The interaction between the actuators and the flexure-based mechanism is extensively investigated based on the established model.

It is well established that DNA methylation is extensively involved in gene imprinting, X inactivation and development.

Cancer pain continues to be extensively undertreated, despite established guidelines.

Market gardening is extensively practiced.