Sentence examples for is expected to inhibit from inspiring English sources
The inhibition of EMMPRIN in melanoma can represent an alternative therapeutic strategy as it is expected to inhibit cell growth and invasion through the simultaneous inhibition of the VEGFR-2/VEGF system and the matrix degrading proteases and possibly other tumor promoting HIF-2α targets.
If the inhibition is reciprocal, then SCR121TT is expected to inhibit endogenous SCR+ activity and SCR+121TT is expected to inhibit endogenous SCR activity, as observed with SCR13A.
The inhibition of PI3K will directly affect Akt activity, which is involved in cell death and survival through several targets such as Bad, whereas the inhibition of mTOR, which acts downstream of Akt, is expected to inhibit proliferation but not apoptosis [ 28].
The presence of the dendron group induces self-assembling into a columnar structure, due to an exo-recognition of the side-chain dendrons, while the benzoyl group is expected to inhibit polymer crystallinity.
At 2 mM caffeine is expected to inhibit ATM but not ATR [29].
Constitutive activity of the HH signaling pathway, such as that in Ptc1−/−UB kidneys, is expected to inhibit the formation of both Gli2 and Gli3 repressor isoforms.
Increasing the concentration of other divalent cations would be expected to inhibit Cd2+ influx due to reduced plasma membrane electronegativity [ 28], non-competitive inhibition of influx by a variety of cations [ 19, 24], or direct competition for specific cation transporters such as observed between Cd2+ and Zn2+ [ 11, 18].
Thus, SL1067 would not be expected to inhibit the activity of IL-1Ra and the two ligands may act synergistically to prevent IL-1RI signal activation.
The efflux of Ca2+ from the SR leads to the accumulation of a transient negative potential within the SR/ER lumen, which would be expected to inhibit the process of the subsequent release of Ca2+ (refs 14, 15, 16).
The initial burst and subsequent long-term sustained local delivery of effective amounts of gentamicin from the antimicrobial sleeves would be expected to inhibit bacterial colonization on external fixation pins and wires.
