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Since selection is exclusively detectable in risk alleles within some moderately associated regions, it may be reasonable to up-weight the importance of these kinds of SNPs for follow-up deep sequencing and functional validation.
However, unlike canonical GPCRs, OA1 is not localized to the cell surface, but is exclusively detectable on the membrane of intracellular organelles, namely late-endosomes/lysosomes and melanosomes (19– 219.
As yet, only a few studies have used antibodies against EpCAM's intracellular domain in cancer tissue, showing that nuclear or cytoplasmic staining is exclusively detectable in tumours, but not in normal tissue [ 14, 34, 35].
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Proteins of ∼60 and 70 kD were exclusively detectable in the EphA2 and EphA4 lanes (Fig. 3b).
Strikingly, high frequencies of iNOS+ and TNF+ cells were exclusively detectable in the Tip-DC and IFNβ/YFP+ cell sample with the YFP+ cells showing even the highest frequencies of both iNOS and TNF producing cells (Figure 5E).
Protein of B-FABP was exclusively detectable in the Caki-2 cells.
In addition, a positive correlation between levels of FBP1, FBP3 and c-Myc was exclusively detectable in RCC.
Furthermore, the expression of a fragment of mtDNA TOP1 was exclusively detectable in SScFib+ patients, including two patients who were negative for anti-Scl70 serum antibodies.
These mRNA data corresponded with the western blot analyses as L-FABP was exclusively detectable in all (14) normal renal tissue lysates but not in RCC samples.
The western blot signal was exclusively detectable under reducing conditions suggesting an incorporation of Cnidoin into the disulphide-linked capsule wall polymer similar to NCol-1 and NOWA [ 13, 26].
They also demonstrated that latent TGF-β, produced by a variety of BM cells, was broadly distributed within BM, while, active TGF-β was exclusively detectable in glial cells that lay in parallel with blood vessels.
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