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Expression of green fluorescent protein (GFP -tagged versions of squalene synthase (SQS) in onion epidermal cells demonstrated that SQS1 is tarGFP -taggede endoplasmic reticulum (ER) membrane and that this location is exclusiversionsendent of the presqualene the synthaseerminal hydrophobic tranSQSembrane domain (Busquets et al. 2008).
To our knowledge, this reaction is exclusively dependent on IRE1α activity and is not detected in IRE1α-deficient cells [18].
First, L. paracasei's activity is exclusively dependent on a soluble mediator while S layer proteins are also present on the surface of the bacterium.
Disruption of all three Dnmt genes in mouse embryonic stem (ES) cells abolishes CpG methylation [9] demonstrating that CpG methylation is exclusively dependent on these enzymes.
In contrast to these two intracellular pathogens, the enhanced killing of B. mallei by IFNγ-primed macrophages is exclusively dependent on the expression of functional iNOS.
Since the dominant-negative effect of N-WASP on receptor-mediated endocytosis is exclusively dependent on the PRD [27], i.e. the binding interface of Abp1, Abp1 might also integrate N-WASP functinto into endocytosis.
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With the limitations of the currently available evidence, it seems safest to assume that Musashi and CPEB both contribute to the polyadenylation of early mRNAs and that some mRNAs may be exclusively dependent on one or the other.
The anatomical changes created with different types of procedures lead to variable weight loss and improvement of co-morbidities; however the latter does not appear to be exclusively dependent on the amount of weight loss.
In this context, it is interesting to note that the generation of IL2 was exclusively dependent on the co-stimulation mediated via CD28.
Characterization of mRNA levels of chemokines in the lung revealed that the expression of eotaxin-1 and -2 were exclusively dependent on STAT6.
The identification of IKKα, also known as CHUK, was unexpected as peptidoglycan recognition via Nod1 triggers the canonical NF-κB pathway, and was, therefore, thought to be exclusively dependent on IKKβ and NEMO.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com