The phrase 'is essential in regulating' is correct and usable in written English.
This phrase is commonly used to draw attention to the importance of something in a particular situation. For example, "Having good communication skills is essential in regulating the workflow of any business."
This co-regulation is essential in regulating a complex cell signaling network, and is more efficient than the regulatory pattern mediated by discrete miRNAs [40], [41].
Liberal internationalists disagree, arguing that, although far from perfect, it is essential in regulating international behaviour and in strengthening liberal norms.
The ubiquitin proteasome system (UPS) is essential in regulating myriad aspects of protein functions.
Dental follicle (DF) is essential in regulating bone formation for tooth eruption.
Transforming growth factor-β is essential in regulating extracellular matrix gene expression and is dependent on Smad3, an intracellular mediator/transcription factor.
VEGFA is essential for early development of the vasculature to the extent that inactivation of even a single allele of the VEGFA gene results in embryonic lethality[14, 15]; furthermore, VEGFA is essential in regulating postnatal muscle capillarity.
Cell adhesion molecules govern leukocyte-endothelial cell (EC) interactions that are essential in regulating leukocyte recruitment, adhesion, and transmigration in areas of inflammation.
For example, the glutamate-cysteine ligase and SLC7A11 are essential in regulating the synthesis of glutathione, a very powerful endogenous antioxidant [39].
These observations suggest that the relative ratio of cystatin C to cathepsins in tumor tissues in situ, and not solely the proteases or inhibitors or those in the circulation, are essential in regulating tumor growth.
Astrocytes are essential in regulating neuronal function and support, and participate in neurogenesis [10], synaptic transmission [11], brain repair [12], and in the formation and preservation of the blood-brain barrier [13].
Next, we analysed activation of calcium handling proteins that are essential in regulating calcium transient amplitude.
