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Heat shock protein 90 (Hsp90) is an abundant and highly conserved molecular chaperone that is essential for viability in eukaryotes.
Clr6 is essential for viability and regulates heterochromatin silencing and gene activity at euchromatin (Bjerling et al., 2002; Nicolas et al., 2007).
Incorporation of lipopolysaccharide (LPS) into the outer membrane of Gram-negative bacteria is essential for viability, and is accomplished by a two-protein complex called LptDE.
SLD1 is essential for viability, while SLD2 is not.
Unlike S. cerevisiae ESC2, rad60 is essential for viability [28].
The ufd of yeast Uba2 is essential for viability [19].
In budding yeast, Spc105p is essential for viability [8].
We show that SLD1 but not SLD2 is essential for viability.
In some strains, methylation is essential for viability of the pathogen [30], [31].
TAH18 is an uncharacterized gene in yeast, which is essential for viability.
CK2 is essential for viability [21] and plays a critical role in tumor development [22].
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