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However, ermelin was cloned and expressed and found to locate in the endoplasmic reticulum and not the plasma membrane [ 42], suggesting that N-terminal cleavage is essential for the relocation of ZIP6 to the plasma membrane as it may display an essential signal for trafficking to the plasma membrane.
Collectively, these data indicate that the COPI trafficking machinery is essential for the ER relocation of GalNAc-Ts.
This relocation required the 3′ untranslated region (UTR), which is essential for efficient messenger RNA processing and export, consistent with an accompanying report6.
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This is essential for later.
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