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Ikaros is essential for regulating hematopoiesis through affecting CLP, pro-B, and NKp generation (Yoshida et al., 2010).
Tau protein is the name given to soluble microtubule-associated protein (MAP), which is essential for regulating intracellular transport (Spillantini & Goedert 2013).
The β3 adrenergic receptor (β3AR) is the predominant β subtype in human brown adipocytes and is essential for regulating thermogenic lipolysis.
HIF1, the most widely studied HIF, is essential for regulating the expression of a battery of hypoxia-responsive genes involved in the adaptive and cell death responses.
While it is widely accepted that the rodent β3-adrenoceptor is essential for regulating fat metabolism, its role in human BAT is still under debate (Arch and Wilson, 1996).
The precise temporal control of neuronal action potentials is essential for regulating many brain functions.
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This diversity might be essential for regulating sequential processing of substrates.
Conversely, the resilience of infected macrophages to pathogen-induced damage may be essential for regulating inflammation and immune responses to S. aureus.
Thymus-derived (naturally occurring) regulatory T cells (Treg) are essential for regulating peripheral autoimmune tolerance and thereby inflammation in the context of infection, autoimmunity and transplant rejection [1].
Overall, these site-directed mutation analyses revealed that the CREB site located at -962 and the E2F-1 site located at −685 within the AP-2α promoter region, are essential for regulating AP-2α transcription.
Their balance may be essential for regulating programmed cell death.
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