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Future studies should comprehensively examine the metal bioavailability in aquatic sediments, because this factor is essential for interactions between the abiotic and biotic components of an aquatic ecosystem [2].
ATP processing by MutL is essential for interactions with MutH and UvrD [4], [13].
The G domain is highly conserved, typical of all GTPases [ 19], and the C domain is essential for interactions with eRF1 [ 11, 61, 62].
The skin constitutes a key interface in the development of vector-borne diseases, and vectors' saliva is essential for interactions between arthropod, parasite, and host.
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It is essential for interaction of the IAP proteins with pro-apoptotic proteins, including the caspase family of death proteases.
Such a flexibility, which resides in the stacked HEAT repeats, is essential for interaction with RanGTP or with NPCs.
Using domain dissection and cross-linking mass spectrometry, we identified a unique region of Pih1p that is essential for interaction with Rvb1p/Rvb2p.
Typically, tubulin inhibitors that bind to the colchicine binding site bear the trimethoxyphenyl (TMP) moiety which is essential for interaction with tubulin.
These results show that optineurin is essential for interaction of CYLD with ubiquitinated RIP.
The DNA binding domain is essential for interaction with the viral origin of plasmid replication (OriP) [10].
For example, the TSP-1 domain of PfTRAP is essential for interaction with the sulfated glycoconjugates of hepatocytes, and the PAN domain of TgMIC4 is crucial for host-cell binding [35], [36].
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