Children are thought to be especially efficacious because of their innocence, although a cynic might note that they are generally easier to find and capture and do not have the physical strength to fight their attackers.
Additionally, PRSK was especially efficacious for Spanish speaking participants, who improved more than English speakers.
IL-12-based immunotherapy could be especially efficacious in cancer patients with inherited defects of IL-12 production [ 187] or with downregulated expression of IL-12 [ 188].
Taken together, these data suggest that CBT might be especially beneficial in patients with high levels of cognitive maladaptation to the pain and high affective distress, whereas OBT might be especially efficacious in patients with high levels of pain behaviours and low physical functioning.
19 If, as Buonocore et al propose, dietary antioxidants can reduce the adverse effects of reactive oxygen species on skin aging, antioxidant substances and bioactive food compounds administered at pharmacological doses in combination with TAZ and GAAF could be especially efficacious.
Since preclinical studies had demonstrated that dual inhibition of the VEGF and PDGF signaling pathways provide greater antitumor activity than inhibition of either pathway alone [ 24, 25], it was hypothesized that the addition of the multitargeted TKI sunitinib to a trastuzumab-based regimen would be especially efficacious.
This is especially relevant with the growing pipeline of highly efficacious and curative, but cost-prohibitive, treatments for HCV infection.
"Her Catholic friends believed her prayers to be particularly efficacious," Stannard writes.
Speed humps have been found to be efficacious in terms of harm minimization, and are especially appropriate in areas with a high concentration of vulnerable road users.
As such, developing efficacious yet cost-effective outpatient programs that provide acute care, such as partial hospitalization and intensive outpatient programs, may be especially critical for adolescents with NSSI.
