In clinical practice there are occasions where antipsychotic dose is escalated more quickly than would be seen routinely.
"It's escalating more and more to the point where law enforcement is not really concerned with human life," he added.
The doses of docetaxel and cisplatin with concurrent standard radiotherapy (60 Gy in 6 weeks) were escalated more than we expected in the phase I portion.
Therapy was escalated more often in patients receiving antimicrobials not in compliance with guideline recommendations (125 of 245, 51%) than in patients treated in compliance with guidelines (298 of 762, 39.1%; P < 0.01).
If the dosing titration of the study drugs had been escalated more rapidly, the need for rescue medication could have been decreased; ⓘ The dropout rate was relatively high, and the missing data caused by dropouts could affect the result of this study.
BEIRUT — The humanitarian crisis inside Syria is escalating rapidly with more than 9 million people — about 40% of the population — in dire need as winter approaches and agencies find it increasingly difficult to deliver aid inside the war-ravaged nation, the United Nations warns.
The spat between O'Brien, who owns 26% of INM, and the O'Reilly family, with 2% more, is escalating despite the fact that O'Brien has three representatives on the 10-person INM board.
The crisis is escalating, the country is becoming more polarised and more radicalised, says Annan.
"Homelessness in major cities is escalating," the article said, "as more laid-off workers already living paycheck to paycheck wind up on the streets or in shelters".
Running the city is costing more and is escalating, but the local economy is beginning to recover and revenue is up, according to City Manager John Pietig.
Fighting erupted a month ago and is escalating, particularly in northern provinces where more than 100,000 people have fled their homes.
