In addition, the rate of glucose-stimulated proinsulin synthesis was enhanced, consistent with a defect in the ability to properly attenuate proinsulin mRNA translation.
Aerobic glycolysis was enhanced, consistent with a suppression of the Warburg phenotype, which was identified by shRNA screening as one of the essential determinants of HAMLET sensitivity in tumour cells.
In fact, sumoylation appeared to be slightly enhanced, consistent with the prolonged residence of PARP-1 on DNA upon inhibition.
ISSUE: The practice of infection control and prevention requires immediate access to current pertinent information and is enhanced by consistent interaction with infection control colleagues.
In the absence of Rab3 GAP, the RAB-3 synaptic enrichment is enhanced, which is consistent with the role of Rab3 GAP in assisting GTP hydrolysis.
When AICAR activates AMPK, we show that the mRNA expression of ubiquitin E3 ligases is enhanced, which is consistent with a previous study [ 6].
Adherence is enhanced through consistent adherence support.
In Gria4 mutants, synaptic excitation of inhibitory reticular thalamic neurons is enhanced, with increased duration of synaptic responses consistent with what might be expected from reduction of the kinetically faster subunit of AMPA receptors encoded by Gria4.
Specifically, we have shown that the duplication state of a gene's neighbors has a strong impact on the probability of retention following WGD and that this effect is enhanced at higher connectivity, which is consistent with the hypothesis of a selective drive to maintain stoichiometric balance between interacting proteins.
