Your English writing platform
Discover LudwigExact(7)
Although Nanos3 is transcribed in both cell lineages, it is efficiently translated only in the germ lineage.
These results indicated that endocanΔ2 mRNA is primate specific, and is efficiently translated in HUVEC in a 14 kDa protein.
So, we designed an mRNA that is efficiently translated with a peak of transposase production 18 h post-transfection without additional release of the molecule.
For these mRNAs at least one of the uORFs is efficiently translated under normal conditions and is longer than 20 codons.
These data suggest that Wnt pathway activation is efficiently translated into β-catenin transcriptional activation only in GBM stem-like cells.
The first of four uORFs within the GCN4 5′ leader is efficiently translated under both good nutritional and starvation conditions and establishes a "reinitiation mode of translation" 14 for all downstream initiation codons 12, 13.
Similar(52)
We previously reported that the mRNAs of ADH7 and BDH2, which encode putative NADPH- and NADH-dependent alcohol dehydrogenases, respectively, were efficiently translated even with translation repression in response to severe vanillin stress.
In vitro translation studies indicated that the mutant polyprotein was efficiently translated and was processed as expected.
Considering that TATA genes are associated with positive translational features we would expect these highly transcribed genes to be efficiently translated.
It appears that Poly-Ribo-Seq detects translation of two types of smORF: (a) 'longer' smORFs that are efficiently translated producing peptides ∼80 aa possessing bioinformatic hallmarks of peptide function; and (b) 'dwarf' smORFs translated from ncRNAs and 5′-UTRs, which are in general shorter (∼20 aa), less efficiently translated, and missing such bioinformatic and molecular markers.
Interestingly, EJCs stimulate mRNA translation, which raises the intriguing question of how intronless KSHV transcripts are efficiently translated.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com