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Chemotherapy alone is associated with high toxicity and poor overall survival benefit with evidence to suggest chemotherapy is efficacious when used as part of multimodality therapy.
The aim of this literature search is to establish if metformin is efficacious when given to clomiphene citrate (CC resistant polycystic ovary syndrome (PCOS) patients.
Although the vaccine is efficacious when tested in an experimental setting, policymakers are more likely to use this vaccine after receiving evidence demonstrating protection when delivered to communities using local health department staff, cold chain equipment, and logistics.
Importantly, as a step towards potential clinical translation, we have determined that host Th2-type cell adoptive transfer is efficacious when used in combination with calcineurin inhibitor therapy, which remains the standard of care therapy.
Although hardly ground-breaking, this study demonstrates that IPV is efficacious when compared with conventional physiotherapy.
Cisplatin is still the most active drug for NSCLC and is efficacious when combined with paclitaxel.
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Prescription nail lacquers like ciclopirox have been clinically tested and approved by the Food and Drug Administration, and shown to be efficacious when used as directed, though not as effective as oral drugs; over-the-counter topicals are also available but have not been tested.
Although comprehensive school-based physical activity interventions are efficacious when tested under research conditions, they often require adaptation in order for implementation at scale.
Compound 39 was highly potent versus PDE10A (IC50 = 1.0 nM), demonstrated high selectivity (>1000-fold >1000-foldther PDEs against efficaciotherhen dosed orally in a rat model of PDEshosis, PCP-induced hyperlocomotion with andEC50 of 1 mg/kg.
C3d-PA/IFA was efficacious when administered either i.p. or s.c., and in adolescent mice lacking a fully mature B cell compartment.
Paclitaxel is an established chemotherapeutic drug and has been shown to be efficacious when conjugated to various anti-cancer agents [51].
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