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Clinically, the use of oxaliplatin is efficacious only when combined with other agents such as 5-fluorouracil (5-FU) and leucovorin (LV).
The issue was whether the supernatural grace in question is efficacious by itself, in other words, intrinsically efficacious, or whether it is efficacious only by virtue of the independent, divinely foreknown cooperation of the one who receives the grace (Vansteenberghe 1928, #2154 65).
Moreover, while current antiretroviral therapy is efficacious only if applied with continuity, it is of utter interest to study its effect on the dynamics of the virus; by simulating on a computer the infection, before, during and after the therapy, we can get insights otherwise difficult or even impossible to be deduced in vivo.
As treatment is efficacious only for those patients who are diagnosed sufficiently early in the disease process, a significant reduction in patient mortality may result from earlier detection of lung cancer, including combinations of biomarkers with spiral CT imaging [ 2].
If this subtype represents only a fraction of the patient population, and if the drug is efficacious only against this specific subtype, then the response rate in the clinic will be significantly lower.
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If a single property is both mental and physical, Completeness and No Overdetermination force us to say that it's efficacious only qua physical, not qua mental.
The evidence is mounting, however, that RBC transfusions are efficacious only when oxygen delivery is compromised.
6, 7 Chloroquine was commonly available raising concern that this antimalarial may be used by private outlets to treat falciparum malaria when it is known to be efficacious only against for P. vivax, P. ovale, and P. malariae.
These details reflect the recognition that specific treatments may be efficacious only within a limited range of individuals depending on such factors as their age, sex, problem severity, socioeconomic status, and ethnicity [ 82].
Approval criteria were based on post hoc reanalysis of PROWESS by the FDA; DrotAA was efficacious only in the sickest patients with severe sepsis - those with multiorgan failure and Acute Physiologic and Chronic Health Evaluation (APACHE) score ≥25 [ 3].
Being directed at TLR4, these therapies may be efficacious only in bacterial Gram-negative sepsis, and their effectiveness will thus be critically dependent on the nature of the infecting organism.
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