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However, IL-6 is highly abundant in undifferentiated tumour cells and is effectively stimulated by IL-1β.
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That is, pollutant biodegradation could be effectively stimulated through operation of ES-accumulated MFCs.
Together, these data indicate that innate immune resistance to influenza can be effectively stimulated, and suggest that ineffective rather than excessive inflammation is the major cause of mortality in influenza pneumonia.
In this case, it is particularly important to model the expected field distributions of the NIBS-induced tissue current in the brain and to estimate which brain regions are effectively stimulated by NIBS based on the calculated field distributions [58].
Importantly, these results demonstrate that T cells responding to native tumor antigens can be effectively stimulated to prevent tumor growth, provided they are activated through the TCR by the appropriate signal.
Collectively, these sorts of actions suppress the immune system, so it cannot be effectively stimulated and cannot eliminate tumor cells, thus allowing some tumor cells to escape and metastasize.
Mice undergoing dendritic cell therapy had more CD4+ T cells in tumor-draining lymph nodes and tumors and a higher fraction of CD4+ T cells expressed an activated phenotype what shows that dendritic cells were effectively stimulating Ep63K-specific T cells.
However, noncutaneous melanocytes, which travel a dorsal-ventral route to the inner ear and the iris, are less sensitive to KIT signaling, likely a consequence of lower KIT cell surface receptor density, and are more effectively stimulated by endothelin 3 (EDN3) or hepatocyte growth factor (HGF) than by KIT (Aoki et al. 2009).
Thus, phagocytosis in immature DC was most effectively stimulated by H-1PV-induced melanoma cell lysates.
Meniscus cells embedded in 3D collagen scaffolds are most effectively stimulated to express and produce chondrocyte-like tissues, abundant in collagen type II and proteoglycan, when cultured under normal oxygen tension.
CN is effectively treated with granulocyte colony stimulating factor (G-CSF), which is known to interfere with apoptosis in neutrophil precursors and to consequently increase the circulating neutrophil level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com